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OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids

Recent discoveries in the field of innate immunity have highlighted the existence of a family of nucleic acid-sensing proteins that have similar structural and functional properties. These include the well-known oligoadenylate synthase (OAS) family proteins and the recently identified OAS homologue...

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Détails bibliographiques
Publié dans:Nat Rev Immunol
Auteurs principaux: Hornung, Veit, Hartmann, Rune, Ablasser, Andrea, Hopfner, Karl-Peter
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7097587/
https://ncbi.nlm.nih.gov/pubmed/25033909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3719
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