cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Detection of cytoplasmic DNA represents one of the most fundamental mechanisms of the innate immune system to sense the presence of microbial pathogens(1). Moreover, erroneous detection of endogenous DNA by the same sensing mechanisms has an important pathophysiological role in certain sterile infla...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Ablasser, Andrea, Goldeck, Marion, Cavlar, Taner, Deimling, Tobias, Witte, Gregor, Röhl, Ingo, Hopfner, Karl-Peter, Ludwig, Janos, Hornung, Veit
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143541/
https://ncbi.nlm.nih.gov/pubmed/23722158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12306
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki