Bacterial Cyclic Dinucleotides and the cGAS–cGAMP–STING Pathway: A Role in Periodontitis?

Host cells can recognize cytosolic double-stranded DNAs and endogenous second messengers as cyclic dinucleotides—including c-di-GMP, c-di-AMP, and cGAMP—of invading microbes via the critical and essential innate immune signaling adaptor molecule known as STING. This recognition activates the innate...

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Detalhes bibliográficos
Publicado no:Pathogens
Main Authors: Elmanfi, Samira, Yilmaz, Mustafa, Ong, Wilson W. S., Yeboah, Kofi S., Sintim, Herman O., Gürsoy, Mervi, Könönen, Eija, Gürsoy, Ulvi K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226932/
https://ncbi.nlm.nih.gov/pubmed/34070809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens10060675
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