Dual Action Calcium-Sensing Receptor Modulator Unmasks Novel Mode-Switching Mechanism

[Image: see text] Negative allosteric modulators (NAMs) of the human calcium-sensing receptor (CaSR) have previously failed to show efficacy in human osteoporosis clinical trials, but there is now significant interest in repurposing these drugs for hypocalcemic disorders and inflammatory lung diseas...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:ACS Pharmacol Transl Sci
मुख्य लेखकों: Gregory, Karen J., Kufareva, Irina, Keller, Andrew N., Khajehali, Elham, Mun, Hee-Chang, Goolam, Mahvash A., Mason, Rebecca S., Capuano, Ben, Conigrave, Arthur D., Christopoulos, Arthur, Leach, Katie
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Chemical Society 2018
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089027/
https://ncbi.nlm.nih.gov/pubmed/32219206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.8b00021
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