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Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2
In this study we investigate the ability of ethanol-inducible CYP2E1 to interact with other cytochrome P450 species and affect the metabolism of their substrates. As a model system we used CYP2E1-enriched human liver microsomes (HLM) obtained by incorporation of purified CYP2E1. Using a technique ba...
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| Gepubliceerd in: | Biochem J |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7085345/ https://ncbi.nlm.nih.gov/pubmed/31750875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190532 |
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