Towards a systems approach to the human cytochrome P450 ensemble: Interactions between CYP2D6 and CYP2E1 and their functional consequences

Functional cross-talk among human drug-metabolizing cytochromes P450 through their association is a topic of emerging importance. Here we studied the interactions of human CYP2D6, a major metabolizer of psychoactive drugs, with one of the most prevalent human P450 enzymes, ethanol-inducible CYP2E1....

Full description

Saved in:
Bibliographic Details
Published in:Biochem J
Main Authors: Davydov, Dmitri R., Davydova, Nadezhda Y., Rodgers, John T., Rushmore, Thomas H., Jones, Jeffrey P.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798876/
https://ncbi.nlm.nih.gov/pubmed/28904078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170543
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items