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Dual regulation of p53 by the ribosome maturation factor SBDS

The Shwachman-Bodian Diamond syndrome (SBDS)-associated gene, SBDS, is involved in rRNA synthesis and ribosome maturation, but the role of SBDS in cancer is largely elusive. In this study, we found that SBDS is often overexpressed or amplified in human cancers, and high level of endogenous SBDS is s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Hao, Qian, Wang, Jieqiong, Chen, Yajie, Wang, Shanshan, Cao, Mingming, Lu, Hua, Zhou, Xiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083877/
https://ncbi.nlm.nih.gov/pubmed/32198344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2393-4
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