Wird geladen...

Ribosomal Protein S14 Unties the MDM2-p53 Loop Upon Ribosomal Stress

The MDM2-p53 feedback loop is crucially important for restricting p53 level and activity during normal cell growth and proliferation, and is thus subjected to dynamic regulation in order for cells to activate p53 upon various stress signals. Several ribosomal proteins, such as RPL11, RPL5, RPL23, RP...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhou, Xiang, Hao, Qian, Liao, Jun-ming, Zhang, Qi, Lu, Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736832/
https://ncbi.nlm.nih.gov/pubmed/22391559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.63
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!