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Ribosomal Protein S14 Unties the MDM2-p53 Loop Upon Ribosomal Stress
The MDM2-p53 feedback loop is crucially important for restricting p53 level and activity during normal cell growth and proliferation, and is thus subjected to dynamic regulation in order for cells to activate p53 upon various stress signals. Several ribosomal proteins, such as RPL11, RPL5, RPL23, RP...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736832/ https://ncbi.nlm.nih.gov/pubmed/22391559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.63 |
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