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Ribosomal Protein S14 Negatively Regulates c-Myc Activity

The ribosomal gene RPS14 is associated with the cancer-prone 5q-syndrome, which is caused by an interstitial deletion of the long arm of human chromosome 5. Previously, we found that ribosomal protein S14 (RPS14) binds to and inactivates MDM2, consequently leading to p53-dependent cell-cycle arrest...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhou, Xiang, Hao, Qian, Liao, Jun-ming, Liao, Peng, Lu, Hua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724636/
https://ncbi.nlm.nih.gov/pubmed/23775087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.445122
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