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Ribosomal Protein L11 Associates with c-Myc at 5 S rRNA and tRNA Genes and Regulates Their Expression

The c-Myc oncoprotein promotes cell growth by enhancing ribosomal biogenesis. Overexpression of c-Myc and aberrant ribosomal biogenesis lead to deregulated cell growth and tumorigenesis. Hence, c-Myc activity and ribosomal biogenesis must be tightly coordinated during normal homeostasis. We previous...

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Bibliografske podrobnosti
Main Authors: Dai, Mu-Shui, Sun, Xiao-Xin, Lu, Hua
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857078/
https://ncbi.nlm.nih.gov/pubmed/20194507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056259
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