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Ribosomal Protein S14 Negatively Regulates c-Myc Activity

The ribosomal gene RPS14 is associated with the cancer-prone 5q-syndrome, which is caused by an interstitial deletion of the long arm of human chromosome 5. Previously, we found that ribosomal protein S14 (RPS14) binds to and inactivates MDM2, consequently leading to p53-dependent cell-cycle arrest...

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Main Authors: Zhou, Xiang, Hao, Qian, Liao, Jun-ming, Liao, Peng, Lu, Hua
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724636/
https://ncbi.nlm.nih.gov/pubmed/23775087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.445122
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