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Dual regulation of p53 by the ribosome maturation factor SBDS

The Shwachman-Bodian Diamond syndrome (SBDS)-associated gene, SBDS, is involved in rRNA synthesis and ribosome maturation, but the role of SBDS in cancer is largely elusive. In this study, we found that SBDS is often overexpressed or amplified in human cancers, and high level of endogenous SBDS is s...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Hao, Qian, Wang, Jieqiong, Chen, Yajie, Wang, Shanshan, Cao, Mingming, Lu, Hua, Zhou, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083877/
https://ncbi.nlm.nih.gov/pubmed/32198344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2393-4
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