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Dual regulation of p53 by the ribosome maturation factor SBDS

The Shwachman-Bodian Diamond syndrome (SBDS)-associated gene, SBDS, is involved in rRNA synthesis and ribosome maturation, but the role of SBDS in cancer is largely elusive. In this study, we found that SBDS is often overexpressed or amplified in human cancers, and high level of endogenous SBDS is s...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Hao, Qian, Wang, Jieqiong, Chen, Yajie, Wang, Shanshan, Cao, Mingming, Lu, Hua, Zhou, Xiang
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083877/
https://ncbi.nlm.nih.gov/pubmed/32198344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2393-4
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