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Mitochondrial ClpX activates an essential biosynthetic enzyme through partial unfolding
Mitochondria control the activity, quality, and lifetime of their proteins with an autonomous system of chaperones, but the signals that direct substrate-chaperone interactions and outcomes are poorly understood. We previously discovered that the mitochondrial AAA+ protein unfoldase ClpX (mtClpX) ac...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7077987/ https://ncbi.nlm.nih.gov/pubmed/32091391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54387 |
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