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Mitochondrial ClpX activates an essential biosynthetic enzyme through partial unfolding

Mitochondria control the activity, quality, and lifetime of their proteins with an autonomous system of chaperones, but the signals that direct substrate-chaperone interactions and outcomes are poorly understood. We previously discovered that the mitochondrial AAA+ protein unfoldase ClpX (mtClpX) ac...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kardon, Julia R, Moroco, Jamie A, Engen, John R, Baker, Tania A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077987/
https://ncbi.nlm.nih.gov/pubmed/32091391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54387
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