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RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation
Mediator of IRF3 activation (MITA, also named as STING/ERIS/MPYS/TMEM173), is essential to DNA virus- or cytosolic DNA-triggered innate immune responses. In this study, we demonstrated the negative regulatory role of RING-finger protein (RNF) 90 in innate immune responses targeting MITA. RNF90 promo...
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| Yayımlandı: | PLoS Pathog |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7069649/ https://ncbi.nlm.nih.gov/pubmed/32126128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008387 |
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