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FoxO1 Negatively Regulates Cellular Antiviral Response by Promoting Degradation of IRF3
Viral infection causes activation of the transcription factor IRF3, which is critical for production of type I interferons (IFNs) and innate antiviral immune response. How virus-induced type I IFN signaling is controlled is not fully understood. Here we identified the transcription factor FoxO1 as a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3642307/ https://ncbi.nlm.nih.gov/pubmed/23532851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.444794 |
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