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IFITM3 inhibits virus-triggered induction of type I interferon by mediating autophagosome-dependent degradation of IRF3

Interferon-induced transmembrane protein 3 (IFITM3) is a restriction factor that can be induced by viral infection and interferons (IFNs). It inhibits the entry and replication of many viruses, which are independent of receptor usage but dependent on processes that occur in endosomes. In this study,...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Mol Immunol
Main Authors: Jiang, Li-Qun, Xia, Tian, Hu, Yun-Hong, Sun, Ming-Shun, Yan, Shuang, Lei, Cao-Qi, Shu, Hong-Bing, Guo, Ji-Hua, Liu, Yu
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203713/
https://ncbi.nlm.nih.gov/pubmed/28435159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.15
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