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IFITM3 inhibits virus-triggered induction of type I interferon by mediating autophagosome-dependent degradation of IRF3

Interferon-induced transmembrane protein 3 (IFITM3) is a restriction factor that can be induced by viral infection and interferons (IFNs). It inhibits the entry and replication of many viruses, which are independent of receptor usage but dependent on processes that occur in endosomes. In this study,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Mol Immunol
Hauptverfasser: Jiang, Li-Qun, Xia, Tian, Hu, Yun-Hong, Sun, Ming-Shun, Yan, Shuang, Lei, Cao-Qi, Shu, Hong-Bing, Guo, Ji-Hua, Liu, Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203713/
https://ncbi.nlm.nih.gov/pubmed/28435159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.15
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