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Zebrafish RPZ5 Degrades Phosphorylated IRF7 To Repress Interferon Production

Interferon (IFN) production activated by phosphorylated interferon regulatory factor 7 (IRF7) is a pivotal process during host antiviral infection. For viruses, suppressing the host IFN response is beneficial for viral proliferation; in such cases, evoking host-derived IFN negative regulators would...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Lu, Long-Feng, Zhou, Xiao-Yu, Zhang, Can, Li, Zhuo-Cong, Chen, Dan-Dan, Liu, Shu-Bo, Li, Shun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803274/
https://ncbi.nlm.nih.gov/pubmed/31413136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01272-19
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