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Inhibition of Interferon Regulatory Factor 7 (IRF7)-Mediated Interferon Signal Transduction by the Kaposi's Sarcoma-Associated Herpesvirus Viral IRF Homolog vIRF3

Upon viral infection, the major defense mounted by the host immune system is activation of the interferon (IFN)-mediated antiviral pathway that is mediated by IFN regulatory factors (IRFs). In order to complete their life cycle, viruses must modulate the host IFN-mediated immune response. Kaposi...

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Main Authors: Joo, Chul Hyun, Shin, Young C., Gack, Michaela, Wu, Liguo, Levy, David, Jung, Jae U.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951281/
https://ncbi.nlm.nih.gov/pubmed/17522209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00235-07
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