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Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 4 (vIRF4) Targets Expression of Cellular IRF4 and the Myc Gene To Facilitate Lytic Replication

Besides an essential transcriptional factor for B cell development and function, cellular interferon regulatory factor 4 (c-IRF4) directly regulates expression of the c-Myc gene, which is not only associated with various B cell lymphomas but also required for herpesvirus latency and pathogenesis. Ka...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Hye-Ra, Doğanay, Sultan, Chung, Brian, Toth, Zsolt, Brulois, Kevin, Lee, Stacy, Kanketayeva, Zhansaya, Feng, Pinghui, Ha, Taekjip, Jung, Jae U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911525/
https://ncbi.nlm.nih.gov/pubmed/24335298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02106-13
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