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Negative Elongation Factor-Mediated Suppression of RNA Polymerase II Elongation of Kaposi's Sarcoma-Associated Herpesvirus Lytic Gene Expression

Genome-wide chromatin immunoprecipitation assays indicate that the promoter-proximal pausing of RNA polymerase II (RNAPII) is an important postinitiation step for gene regulation. During latent infection, the majority of Kaposi's sarcoma-associated herpesvirus (KSHV) genes is silenced via repre...

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Detalhes bibliográficos
Main Authors: Toth, Zsolt, Brulois, Kevin F., Wong, Lai-Yee, Lee, Hye-Ra, Chung, Brian, Jung, Jae U.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446579/
https://ncbi.nlm.nih.gov/pubmed/22740393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01012-12
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