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Construction of a Lytically Replicating Kaposi's Sarcoma-Associated Herpesvirus

Karposi's sarcoma-associated herpesvirus (KSHV) is found predominantly in a latent state in most cell types, impeding investigations of the lytic replication cycle. Here, we engineered the cloned KSHV genome, bacterial artificial chromosome 36 (BAC36), to enforce constitutive expression of the...

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Main Authors: Budt, Matthias, Hristozova, Tsvetana, Hille, Georg, Berger, Katrin, Brune, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196422/
https://ncbi.nlm.nih.gov/pubmed/21795351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05071-11
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