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Construction of a Lytically Replicating Kaposi's Sarcoma-Associated Herpesvirus

Karposi's sarcoma-associated herpesvirus (KSHV) is found predominantly in a latent state in most cell types, impeding investigations of the lytic replication cycle. Here, we engineered the cloned KSHV genome, bacterial artificial chromosome 36 (BAC36), to enforce constitutive expression of the...

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Bibliografiske detaljer
Main Authors: Budt, Matthias, Hristozova, Tsvetana, Hille, Georg, Berger, Katrin, Brune, Wolfram
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196422/
https://ncbi.nlm.nih.gov/pubmed/21795351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05071-11
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