Kaposi's Sarcoma-Associated Herpesvirus Transactivator RTA Promotes Degradation of the Repressors To Regulate Viral Lytic Replication

Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV-8) RTA is an important protein involved in the induction of KSHV lytic replication from latency through activation of the lytic cascade. A number of cellular and viral proteins, including K-RBP, have been found to repress RTA...

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Bibliographic Details
Main Authors: Yang, Zhilong, Yan, Zhangcai, Wood, Charles
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268447/
https://ncbi.nlm.nih.gov/pubmed/18216089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02229-07
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