Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 4 (vIRF4) Perturbs the G(1)-S Cell Cycle Progression via Deregulation of the cyclin D1 Gene

Kaposi's sarcoma-associated herpesvirus (KSHV) infection modulates the host cell cycle to create an environment optimal for its viral-DNA replication during the lytic life cycle. We report here that KSHV vIRF4 targets the β-catenin/CBP cofactor and blocks its occupancy on the cyclin D1 promoter...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Lee, Hye-Ra, Mitra, Jaba, Lee, Stacy, Gao, Shou-Jiang, Oh, Tae-Kwang, Kim, Myung Hee, Ha, Taekjip, Jung, Jae U.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702683/
https://ncbi.nlm.nih.gov/pubmed/26491150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01897-15
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky