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KSHV-encoded viral interferon regulatory factor 4 (vIRF4) interacts with IRF7 and inhibits interferon alpha production

Before an infection can be completely established, the host immediately turns on the innate immune system through activating the interferon (IFN)-mediated antiviral pathway. Kaposi’s sarcoma-associated herpesvirus (KSHV) utilizes a unique antagonistic mechanism of type I IFN-mediated host antiviral...

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Publicat a:Biochem Biophys Res Commun
Autors principals: Hwang, Sung-Woo, Kim, DongIk, Jung, Jae U., Lee, Hye-Ra
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490377/
https://ncbi.nlm.nih.gov/pubmed/28342865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.03.101
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