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IFITM3 inhibits virus-triggered induction of type I interferon by mediating autophagosome-dependent degradation of IRF3

Interferon-induced transmembrane protein 3 (IFITM3) is a restriction factor that can be induced by viral infection and interferons (IFNs). It inhibits the entry and replication of many viruses, which are independent of receptor usage but dependent on processes that occur in endosomes. In this study,...

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Detalles Bibliográficos
Publicado en:Cell Mol Immunol
Main Authors: Jiang, Li-Qun, Xia, Tian, Hu, Yun-Hong, Sun, Ming-Shun, Yan, Shuang, Lei, Cao-Qi, Shu, Hong-Bing, Guo, Ji-Hua, Liu, Yu
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203713/
https://ncbi.nlm.nih.gov/pubmed/28435159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.15
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