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Krüppel-like factor 4 negatively regulates cellular antiviral immune response

Viral infection triggers activation of the transcription factors NF-κB and IRF3, which collaborate to induce the expression of type I interferons (IFNs) and elicit innate antiviral response. In this report, we identified Krüppel-like factor 4 (KLF4) as a negative regulator of virus-triggered signali...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Luo, Wei-Wei, Lian, Huan, Zhong, Bo, Shu, Hong-Bing, Li, Shu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711676/
https://ncbi.nlm.nih.gov/pubmed/25531393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.125
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