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ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response
The retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), including RIG-I and melanoma differentiation-associated gene 5 (MDA5), sense cytoplasmic viral RNA and initiate innate antiviral responses. How RIG-I and MDA5 are differentially regulated remains enigmatic. In this study, we identifie...
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| Pubblicato in: | PLoS Pathog |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7162542/ https://ncbi.nlm.nih.gov/pubmed/32251420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008457 |
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