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ECSIT Bridges RIG-I-Like Receptors to VISA in Signaling Events of Innate Antiviral Responses
Upon binding to RNA structures from invading viruses, RIG-I and MDA5 are recruited to mitochondria to interact with VISA and initiate antiviral type I interferon (IFN) responses. How this process is mediated is less understood. In this report, we demonstrate that ECSIT is an essential scaffolding pr...
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| Опубликовано в: : | J Innate Immun |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
S. Karger AG
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6738808/ https://ncbi.nlm.nih.gov/pubmed/25228397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000365971 |
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