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TRIM5α self-assembly and compartmentalization of the HIV-1 viral capsid

The tripartite-motif protein, TRIM5α, is an innate immune sensor that potently restricts retrovirus infection by binding to human immunodeficiency virus capsids. Higher-ordered oligomerization of this protein forms hexagonally patterned structures that wrap around the viral capsid, despite an anomal...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Yu, Alvin, Skorupka, Katarzyna A., Pak, Alexander J., Ganser-Pornillos, Barbie K., Pornillos, Owen, Voth, Gregory A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066149/
https://ncbi.nlm.nih.gov/pubmed/32161265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15106-1
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