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TRIM5α self-assembly and compartmentalization of the HIV-1 viral capsid
The tripartite-motif protein, TRIM5α, is an innate immune sensor that potently restricts retrovirus infection by binding to human immunodeficiency virus capsids. Higher-ordered oligomerization of this protein forms hexagonally patterned structures that wrap around the viral capsid, despite an anomal...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7066149/ https://ncbi.nlm.nih.gov/pubmed/32161265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15106-1 |
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