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Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate

ABSTRACT: Recent data suggest that paternal age can have major impact on reproductive outcomes, and with increased age, there is increased likelihood of chromosomal abnormalities in the sperm. Here, we studied DNA damage and repair as a function of male aging and assessed whether sphingosine-1-phosp...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Reprod Sci
Päätekijät: Stobezki, Robert, Titus, Shiny, Halicka, Dorota, Darzynkiewicz, Zbigniew, Oktay, Kutluk
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer International Publishing 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065969/
https://ncbi.nlm.nih.gov/pubmed/31916095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s43032-019-00098-1
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