Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics

Nuclear factor κB (NF-κB) RelA is the potent transcriptional activator of inflammatory response genes. We stringently defined a list of direct RelA target genes by integrating physical (chromatin immunoprecipitation sequencing [ChIP-seq]) and functional (RNA sequencing [RNA-seq] in knockouts) datase...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ngo, Kim A., Kishimoto, Kensei, Davis-Turak, Jeremy, Pimplaskar, Aditya, Cheng, Zhang, Spreafico, Roberto, Chen, Emily Y., Tam, Amy, Ghosh, Gourisankar, Mitchell, Simon, Hoffmann, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061728/
https://ncbi.nlm.nih.gov/pubmed/32101750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.108
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