Mobilization‐based transplantation of young‐donor hematopoietic stem cells extends lifespan in mice

Mammalian aging is associated with reduced tissue regeneration and loss of physiological integrity. With age, stem cells diminish in their ability to regenerate adult tissues, likely contributing to age‐related morbidity. Thus, we replaced aged hematopoietic stem cells (HSCs) with young‐donor HSCs u...

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Bibliografische gegevens
Gepubliceerd in:Aging Cell
Hoofdauteurs: Guderyon, Michael J., Chen, Cang, Bhattacharjee, Anindita, Ge, Guo, Fernandez, Roman A., Gelfond, Jonathan A. L., Gorena, Karla M., Cheng, Catherine J., Li, Yang, Nelson, James F., Strong, Randy J., Hornsby, Peter J., Clark, Robert A., Li, Senlin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
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Original Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059148/
https://ncbi.nlm.nih.gov/pubmed/32012439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13110
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