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Mitochondrial metabolites extend lifespan
Disruption of mitochondrial respiration in the nematode Caenorhabditis elegans can extend lifespan. We previously showed that long‐lived respiratory mutants generate elevated amounts of α‐ketoacids. These compounds are structurally related to α‐ketoglutarate, suggesting they may be biologically rele...
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| Publicado no: | Aging Cell |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783347/ https://ncbi.nlm.nih.gov/pubmed/26729005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12439 |
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