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The Paradox of Mitochondrial Dysfunction and Extended Longevity

Mitochondria play numerous, essential roles in the life of eukaryotes. Disruption of mitochondrial function in humans is often pathological or even lethal. Surprisingly, in some organisms mitochondrial dysfunction can result in life extension. This paradox has been studied most extensively in the lo...

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Detalhes bibliográficos
Main Authors: Munkácsy, Erin, Rea, Shane L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104296/
https://ncbi.nlm.nih.gov/pubmed/24699406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.03.016
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