DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans

Mitochondrial dysfunction underlies numerous age-related pathologies. In an effort to uncover how the detrimental effects of mitochondrial dysfunction might be alleviated, we examined how the nematode C. elegans not only adapts to disruption of the mitochondrial electron transport chain, but in many...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS Genet
Hlavní autoři: Munkácsy, Erin, Khan, Maruf H., Lane, Rebecca K., Borror, Megan B., Park, Jae H., Bokov, Alex F., Fisher, Alfred L., Link, Christopher D., Rea, Shane L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946786/
https://ncbi.nlm.nih.gov/pubmed/27420916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006133
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky