Single Copy Transgene Integration in a Transcriptionally Active Site for Recombinant Protein Synthesis

For the biomanufacturing of protein biologics, establishing stable cell lines with high transgene transcription is critical for high productivity. Modern genome engineering tools can direct transgene insertion to a specified genomic locus and can potentially become a valuable tool for cell line gene...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Biotechnol J
Hlavní autoři: O’Brien, Sofie A., Lee, Kyoungho, Fu, Hsu-Yuan, Lee, Zion, Le, Tung S., Stach, Christopher S., McCann, Meghan G., Zhang, Alicia Q., Smanski, Michael J., Somia, Nikunj V., Hu, Wei-Shou
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058118/
https://ncbi.nlm.nih.gov/pubmed/30024101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201800226
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky