Tissue- and site-specific DNA recombination in transgenic mice.

We have developed a method of specifically modifying the mammalian genome in vivo. This procedure comprises heritable tissue-specific and site-specific DNA recombination as a function of recombinase expression in transgenic mice. Transgenes encoding the bacteriophage P1 Cre recombinase and the loxP-...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Orban, P C, Chui, D, Marth, J D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49604/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1495975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.15.6861
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