Ligand-activated site-specific recombination in mice.

Current mouse gene targeting technology is unable to introduce somatic mutations at a chosen time and/or in a given tissue. We report here that conditional site-specific recombination can be achieved in mice using a new version of the Cre/lox system. The Cre recombinase has been fused to a mutated l...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Feil, R, Brocard, J, Mascrez, B, LeMeur, M, Metzger, D, Chambon, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38252/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855277/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10887
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