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Tissue- and site-specific DNA recombination in transgenic mice.

We have developed a method of specifically modifying the mammalian genome in vivo. This procedure comprises heritable tissue-specific and site-specific DNA recombination as a function of recombinase expression in transgenic mice. Transgenes encoding the bacteriophage P1 Cre recombinase and the loxP-...

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Bibliografske podrobnosti
Main Authors: Orban, P C, Chui, D, Marth, J D
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC49604/
https://ncbi.nlm.nih.gov/pubmed/1495975
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