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Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice.

Site-specific recombinases are being developed as tools for "in vivo" genetic engineering because they can catalyze precise excisions, integrations, inversions, or translocations of DNA between their distinct recognition target sites. Here it is demonstrated that Flp recombinase can effectively medi...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Hovedforfatter: Dymecki, S M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39212/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8650242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.12.6191
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