Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice.
Site-specific recombinases are being developed as tools for "in vivo" genetic engineering because they can catalyze precise excisions, integrations, inversions, or translocations of DNA between their distinct recognition target sites. Here it is demonstrated that Flp recombinase can effectively medi...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8650242/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.12.6191 |
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