Llwytho...

Relevance of BAC transgene copy number in mice: transgene copy number variation across multiple transgenic lines and correlations with transgene integrity and expression

Bacterial artificial chromosomes (BACs) are excellent tools for manipulating large DNA fragments and, as a result, are increasingly utilized to engineer transgenic mice by pronuclear injection. The demand for BAC transgenic mice underscores the need for careful inspection of BAC integrity and fideli...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chandler, Kelly J., Chandler, Ronald L., Broeckelmann, Eva M., Hou, Yue, Southard-Smith, E. Michelle, Mortlock, Douglas P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110064/
https://ncbi.nlm.nih.gov/pubmed/17882484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-007-9056-y
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