Efficient RNP-directed Human Gene Targeting Reveals SPDEF Is Required for IL-13–induced Mucostasis

Primary human bronchial epithelial cell (HBEC) cultures are a useful model for studies of lung health and major airway diseases. However, mechanistic studies have been limited by our ability to selectively disrupt specific genes in these cells. Here we optimize methods for gene targeting in HBECs by...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Am J Respir Cell Mol Biol
Main Authors: Koh, Kyung Duk, Siddiqui, Sana, Cheng, Dan, Bonser, Luke R., Sun, Dingyuan I., Zlock, Lorna T., Finkbeiner, Walter E., Woodruff, Prescott G., Erle, David J.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055692/
https://ncbi.nlm.nih.gov/pubmed/31596609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0266OC
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker