Epithelial miR-141 regulates IL-13–induced airway mucus production

IL-13–induced goblet cell metaplasia contributes to airway remodeling and pathological mucus hypersecretion in asthma. miRNAs are potent modulators of cellular responses, but their role in mucus regulation is largely unexplored. We hypothesized that airway epithelial miRNAs play roles in IL-13–induc...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Siddiqui, Sana, Johansson, Kristina, Joo, Alex, Bonser, Luke R., Koh, Kyung Duk, Le Tonqueze, Olivier, Bolourchi, Samaneh, Bautista, Rodriel A., Zlock, Lorna, Roth, Theodore L., Marson, Alexander, Bhakta, Nirav R., Ansel, K. Mark, Finkbeiner, Walter E., Erle, David J., Woodruff, Prescott G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8021117/
https://ncbi.nlm.nih.gov/pubmed/33682796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.139019
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