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Epithelial tethering of MUC5AC-rich mucus impairs mucociliary transport in asthma

The development of pathologic mucus, which is not readily cleared from the airways, is an important contributor to the morbidity and mortality associated with asthma. It is not clear how the major airway mucins MUC5AC and MUC5B are organized within the mucus gel or how this gel contributes to airway...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Bonser, Luke R., Zlock, Lorna, Finkbeiner, Walter, Erle, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887179/
https://ncbi.nlm.nih.gov/pubmed/27183390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84910
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