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Epithelial tethering of MUC5AC-rich mucus impairs mucociliary transport in asthma

The development of pathologic mucus, which is not readily cleared from the airways, is an important contributor to the morbidity and mortality associated with asthma. It is not clear how the major airway mucins MUC5AC and MUC5B are organized within the mucus gel or how this gel contributes to airway...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Bonser, Luke R., Zlock, Lorna, Finkbeiner, Walter, Erle, David J.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887179/
https://ncbi.nlm.nih.gov/pubmed/27183390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84910
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