The type 2 asthma mediator IL-13 inhibits SARS-CoV-2 infection of bronchial epithelium

RATIONALE: Asthma is associated with chronic changes in the airway epithelium, a key target of SARS-CoV-2. Many epithelial changes are driven by the type 2 cytokine IL-13, but the effects of IL-13 on SARS-CoV-2 infection are unknown. OBJECTIVES: We sought to discover how IL-13 and other cytokines af...

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Publicado en:bioRxiv
Autores principales: Bonser, Luke R., Eckalbar, Walter L., Rodriguez, Lauren, Shen, Jiangshan, Koh, Kyung Duk, Zlock, Lorna T., Christenson, Stephanie, Woodruff, Prescott G., Finkbeiner, Walter E., Erle, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924269/
https://ncbi.nlm.nih.gov/pubmed/33655249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.25.432762
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