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IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma

Rationale: Quantification of type 2 inflammation provided a molecular basis for heterogeneity in asthma. Non–type 2 pathways that contribute to asthma pathogenesis are not well understood. Objectives: To identify dysregulated pathways beyond type 2 inflammation. Methods: We applied RNA sequencing to...

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Bibliografiska uppgifter
I publikationen:Am J Respir Crit Care Med
Huvudupphovsmän: Bhakta, Nirav R., Christenson, Stephanie A., Nerella, Srilaxmi, Solberg, Owen D., Nguyen, Christine P., Choy, David F., Jung, Kyle L., Garudadri, Suresh, Bonser, Luke R., Pollack, Joshua L., Zlock, Lorna T., Erle, David J., Langelier, Charles, Derisi, Joseph L., Arron, Joseph R., Fahy, John V., Woodruff, Prescott G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Thoracic Society 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811952/
https://ncbi.nlm.nih.gov/pubmed/29064281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201706-1070OC
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