IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma

Rationale: Quantification of type 2 inflammation provided a molecular basis for heterogeneity in asthma. Non–type 2 pathways that contribute to asthma pathogenesis are not well understood. Objectives: To identify dysregulated pathways beyond type 2 inflammation. Methods: We applied RNA sequencing to...

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Bibliografske podrobnosti
izdano v:Am J Respir Crit Care Med
Main Authors: Bhakta, Nirav R., Christenson, Stephanie A., Nerella, Srilaxmi, Solberg, Owen D., Nguyen, Christine P., Choy, David F., Jung, Kyle L., Garudadri, Suresh, Bonser, Luke R., Pollack, Joshua L., Zlock, Lorna T., Erle, David J., Langelier, Charles, Derisi, Joseph L., Arron, Joseph R., Fahy, John V., Woodruff, Prescott G.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2018
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Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811952/
https://ncbi.nlm.nih.gov/pubmed/29064281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201706-1070OC
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