IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma

Rationale: Quantification of type 2 inflammation provided a molecular basis for heterogeneity in asthma. Non–type 2 pathways that contribute to asthma pathogenesis are not well understood. Objectives: To identify dysregulated pathways beyond type 2 inflammation. Methods: We applied RNA sequencing to...

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Bibliographic Details
Published in:Am J Respir Crit Care Med
Main Authors: Bhakta, Nirav R., Christenson, Stephanie A., Nerella, Srilaxmi, Solberg, Owen D., Nguyen, Christine P., Choy, David F., Jung, Kyle L., Garudadri, Suresh, Bonser, Luke R., Pollack, Joshua L., Zlock, Lorna T., Erle, David J., Langelier, Charles, Derisi, Joseph L., Arron, Joseph R., Fahy, John V., Woodruff, Prescott G.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2018
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811952/
https://ncbi.nlm.nih.gov/pubmed/29064281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201706-1070OC
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